Articles in Peer-Reviewed Journals


  1. Marciano, J. M.; Crawford, L.; Mukhopadhyay, L.; Scott, W.; McElroy, A.; McDonough, C. A. Per/polyfluoroalkyl substances (PFASs) in a marine apex predator (white shark, Carcharodon carcharias) in the Northwest Atlantic Ocean. ACS Environmental Au, 2024. DOI: 10.1021/acsenvironau.3c00055


  1. Wallis, D. J.; Barton, K. E.; Knappe, D. R. U.; Kotlarz, N.; McDonough, C. A.; Higgins, C. P.; Hoppin, J. A.; Adgate, J. A. Source apportionment of serum PFASs in two highly exposed communities. STOTEN, 2023855 158842 DOI: 10.1016/j.scitotenv.2022.158842 
  2. Perera, D.; Scott, W.; Smolinski, R.; Mukhopadhyay, L.; McDonough, C. A. Techniques to characterize PFAS burden in biological samples: Recent insights and remaining challenges. Trend in Environmental Analytical Chemistry2023. e00224 DOI: 10.1016/j.teac.2023.e00224


  1. Londhe, K.; Lee, C. S.; McDonough, C. A.; Venkatesan, A. K. The need for testing isomer profiles of perfluoroalkyl substances to evaluate treatment processes. Environ. Sci. Technol. 202256 (22) 15207-15219 DOI:  10.1021/acs.est.2c05518
  2. Koelmel, J.; Stelben, P.; McDonough, C. A.Dukes, D. A.; Aristizabal-Henao, J. J.; Nason, S. L.; Li, Y.; Sternberg, S.; Lin, E.; Beckmann, M.; Williams, A. J.; Draper, J.; Finch, J. P.; Munk, J. K.; Deigl, C.; Rennie, E. E.; Bowden, J. A.; Godri Pollitt, K. J. FluoroMatch 2.0 – Making automated and comprehensive non-targeted PFAS annotation a reality. Analytical & Bioanalytical Chemistry2022. 414 (3) 1201-1215 DOI: 10.1007/s00216-021-03392-7
  3. Charbonnet, J.; McDonough, C. A.; Xiao, F.; Schwichtenberg, T.; Cao, D.; Field, J.; Place, B.; Kaserzon, S.; Helbling, D.; Higgins, C. Non-target identification of per- and polyfluoroalkyl substances by high-resolution mass spectrometry: Increasing and communicating certainty. Environmental Science & Technology Letters. 2022. (6) 473-481 DOI:  10.1021/acs.estlett.2c00206
  4. Koelmel, J.; Stelben, P.; Godri, D.; Qi, J.; McDonough, C. A.; Dukes, D. A.; Aristizabal-Henao, J. J.; Bowden, J. A.; Sternberg, S.; Rennie, E. E.; Godri Pollitt, K. J. Interactive software for visualization of non-targeted mass spectrometry data – FluoroMatch visualizer. Exposome. 2022. Accepted.
  5. McDonough, C. A.; Li, W.; Bischel, H. N.; DeWitt, J. C.; De Silva, A. O. Widening the lens on PFASs: Direct human exposure to perfluoroalkyl acid precursors (pre-PFAAs). Environmental Science & Technology. 2022.  56 (10) 6004-6013 DOI: 10.1021/acs.est.2c00254
  6. Barton, K.; Zell-Baran, L. M.; DeWitt, J. C.; Brindley, S.; McDonough, C. A.; Higgins, C. P.; Adgate, J. L.; Starling, A. P. Cross-sectional associations between serum PFASs and inflammatory biomarkers in a population exposed to AFFF-contaminated drinking water. International Journal of Hygiene and Environmental Health. 113905. DOI: 10.1016/j.ijheh.2021.113905


  1. Narizzano, A. M.; Bohannon, M. E.; East, A. G.; McDonough, C. A.; Choyke, S.; Higgins, C. P.; Quinn, M. J. Patterns in serum toxicokinetics in Peromyscus exposed to PFAS. Environmental Toxicology & Chemistry. 2021. 40 (10) 2886-2898 DOI: 10.1002/etc.5151
  2. McDonough, C. A.; Choyke, S.; Barton, K. E.; Mass, S.; Starling, A. P.; Adgate, J.; Higgins, C. P. Unsaturated PFOS (UPFOS) and other PFASs in human serum and drinking water from an AFFF-impacted community. Environmental Science & Technology. 2021. 
  3. Bradley, P.; Padilla, I.; Romanok, K.; Smalling, K.; Focaziod, M.; Breitmeyer; S.; Mardone, M.; Conleye, J.; Evans, N.; Givens, C.; Gray, J.; Graye, L.; Hartige, P.; Higgins, C.; Hladik, M.; Laneh, R.; Lofinj, K.; McCleskey, R.; McDonough, C. A.; Medlock-Kakaleye, E.; Meppelink, S.; Wais, C.; Wilone, V. Tapwater exposures, predicted effects, and potential role in adverse health outcomes in Puerto Rico, USA. Science of the Total Environment. 2021.
  4. Bradley, P.; Padilla, I.; Romanok, K. M.; Smalling, K. L.; Focazio, M. J.; Breitmeyer, S. E.; Cardon, M. C.; Conley, J. M.; Evans, N.; Givens, C. E.; Gray, J. L.; Gray, E.; Hartig, P. C.; Higgins, C. P.; Hladik, M. L.; Iwanowicz, L. R.; Lane, R. F.; Loftin, K. A.; McCleskey, B.; McDonough, C. A.; Medlock-Kakaley, E.; Meppelink, S. M.; Weis, C. P.; Wilson, V. S. Public and Private Tap water: Comparative Analysis of Contaminant Exposure and Potential Risk, Cape Cod, Massachusetts, USA. Environment International. 2021.
  5. Ali, A. M.; Langberg, H. A.; Hale, S. E.; Kallenborn, R.; Hartz, W. F.; Jenssen, B. M.; Mortensen, A.; Ciesielski, T. M.; McDonough, C. A.; Breedveld, G. D. The fate of poly- and perfluoroalkyl substances in a marine food web influenced by land-based sources in the Norwegian Arctic. RSC Environmental Science: Processes & Impacts. 2021.
  6. McDonough, C. A.; Ward, C.; Hu, Q.; Vance, S.; Higgins, C. P.; DeWitt, J. Immunotoxicity of an electrochemically fluorinated aqueous film-forming foam mixture. Toxicological Sciences. 2021.


  1. McDonough, C. A.; Ward, C.; Hu, Q.; Vance, S.; Higgins, C. P.; DeWitt, J. Immunotoxicity of an electrochemically fluorinated aqueous film-forming foam mixture. Tox. Sci. 2020. 178 (1) 104-114. DOI: 10.1093/toxsci/kfaa138
  2. McDonough, C. A.; Choyke, S.; Ferguson, P. L.; DeWitt, J. C.; Higgins, C. P. Bioaccumulation of novel per/polyfluoroalkyl substances in mice dosed with an aqueous film-forming foam. Sci. Technol. 2020. 54, 5700-5709. DOI: 10.1021/acs.est.0c00234
  3. Bradley, P.; Argos, M.; Kolpin, D.; Meppelink, S.; Romanok, K.; Smalling, K.; Focazio, M.; Allen, J.; Dietze, J.; De Vito, M.; Donovan, A.; Evans, N.; Givens, C.; Gray, J.; Higgins, C.; Hladik, M.; Iwanowicz, L.; Journey, C.; Lane, R.; Laughrey, Z.; Loftin, Z.; McCleskey, R.; McDonough, C.; Medlock-Kakaley, E.; Meyer, M.; Putz, A.; Richardson, S.; Stark, A.; Weis, C.; Wilson, V.; Zehraoui, A. Mixed organic and inorganic tapwater exposures and potential effects in greater Chicago area, USA. Tot. Environ. 2020. 719, 137236. DOI: 10.1016/j.scitotenv.2020.137236
  4. Barton, K.; Starling, A.; Higgins, C. P.; McDonough, C. A.; Calafat, A.; Adgate, J. Sociodemographic and behavioral determinants of serum concentrations of per- and polyfluoroalkyl substances in a community highly exposed to aqueous film-forming foam contaminants in drinking water. J. Hyg. Environ. Health. 2020. 223 (1), 256-266. DOI: 10.1016/j.ijheh.2019.07.012


  1. McDonough, C. A.; Franks, D.; Hahn, M. E.; Lohmann, R. Aryl hydrocarbon-mediated activity of gas-phase ambient air derived from passive sampling and an in vitro bioassay.  Environ. Toxicol. Chem. 2019. 38, 748-759. DOI: 10.1002/etc.4361
  2. Murray, C. C.; Vatankhah, H.; McDonough, C. A.; Nickerson, A.; Hedtke, T. T.; Higgins, C. P.; Bellona, C. L. Removal of per- and polyfluoroalkyl substances using super-fine powder activated carbon and ceramic membrane filtration compared to granular activated carbon. Hazard Mater. 2018. 366, 160-168. DOI: 10.1016/j.jhazmat.2018.11.050


  1. McDonough, C. A.; Guelfo, J. L.; Higgins, C. P. Measuring total PFASs in water: The tradeoff between selectivity and inclusivity. Current Opinion in Environmental Science & Health.  2018. 7, 13-18. DOI: 10.1016/j.coesh.2018.08.005.
  2. McDonough, C. A.; De Silva, A. O.; Sun, C.; Adelman, D.; Soltwedel, T.; Bauerfiend, E.; Muir, D. C. G.; Lohmann, R. Dissolved organophosphate esters in North Atlantic depth profiles and Canadian Arctic surface waters. Environ. Sci. Technol. 2018. 52, 6208-6216. DOI: 10.1021/acs.est.8b01127
  3. Ma, Y.; Adelman, D.; Bauerfeind, E.; Cabrerizo, A.; McDonough, C. A.; Muir, D. C. G.; Soltwedel, T.; Sun, C.; Wagner, C.; Sunderland, E.; Lohmann, R. Concentrations and water mass transport of legacy POPs in the Arctic Ocean. Geophys. Res. Lett. 2018. 45 (23), 12972-12981. DOI: 10.1029/2018GL078759
  4. Bradley, P.; Kolpin, D.; Romanok, K.; Smalling, K.; Focazio, M.; Brown, J.; Cardon, M.; Carpenter, K.; Corsi, S.; De Cicco, L.; Dietze, J.; Evans, N.; Furlong, E.; Givens, C.; Gray, J.; Griffin, D.; Higgins, C.; Hladik, M.; Iwanowicz, L.; Journey, C.; Kuivila, K.; Masoner, J.; McDonough, C. A.; Meyer, M.; Orlando, J.; Strynar, M.; Weis, C.; Wilson, V. Reconnaissance of mixed organic and inorganic chemicals in private and public supply tap waters at selected residential and workplace sites in the U.S. Sci. Technol. 2018, 52 (23), 13972-13985. DOI: 10.1021/acs.est.8b04622


  1. McDonough, C. A.; Puggioni, G.; Helm. P. A.; Muir, D. C. G.; Lohmann, R. Spatial trends and diffusive air-water exchange of organic flame retardants in the lower Great Lakes. Sci. Technol. 2016. 50, 9133-9141. DOI: 10.1021/acs.est.6b02496
  2. McDonough, C. A.; P. A.; Muir, D. C. G.; Puggioni, G.; Lohmann, R. Polycyclic musks in the air and water of the lower Great Lakes: Spatial distribution and volatilization from surface waters. Environ. Sci. Technol. 2016. 50, 11575-11583. DOI: 10.1021/acs.est.6b03657
  3. Liu, Y.; Wang, S.; McDonough, C. A.; Khairy, M.; Muir, D. C. G.; Helm, P.; Lohmann, R. Estimation of uncertainty in air-water exchange flux and gross volatilization loss of PCBs: A case study based on passive sampling in the lower Great Lakes. Sci. Technol. 2016. 50, 10894-10902. DOI: 10.1021/acs.est.6b02891


  1. Liu, Y.; Wang, S.; McDonough, C. A.; Khairy, M. ; Muir, D. C. G. ; Helm, P. ; Lohmann, R. Gaseous and freely dissolved PCBs in the lower Great Lakes based on passive sampling: Spatial trends, sources, and air-water exchange. Environ. Sci. Technol. 2015. 10, 4932-4939. DOI: 10.1021/acs.est.5b04586 


  1. McDonough, C. A.; Khairy, M.; Muir, D. C. G.; Lohmann, R. Significance of population centers as sources of gaseous and dissolved PAHs in the lower Great Lakes. Sci. Technol. 2014. 48, 7789-7797. DOI: 10.1021/es501074r

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